Jonathan Savitz - Faculty & Adjuncts

Jonathan Savitz, PhD

Jonathan Savitz, PhD
Associate Professor of Community Medicine
College of Health Sciences
Community Medicine
Oxley Health Sciences Facility Room LIBR

Education

PhD – University of Cape Town MS – University of Witwatersrand BS – University of Witwatersrand BS – University of the Witwatersrand

Research Interests

Mood Disorders; Psychoneuroimmunology; Infectious Disease in Psychiatry

Publications

Journal Articles

  • Meier , T., Huber , D., Bohorquez-Montoya , L., Nitta , M., Savitz , J., Teague , T., Bazarian , J., Hayes , R., Nelson , L., & McCrea , M. (2020). A Prospective Study of Acute Blood-Based Biomarkers for Sport-Related Concussion.
  • Meier , T., Nitta , M., Teague , T., Nelson , L., McCrea , M., & Savitz , J. (2020). Prospective study of the effects of sport-related concussion on serum kynurenine pathway metabolites.
  • Savitz , J. (2020). The kynurenine pathway: a finger in every pie, 25, 131-147.
  • Brett , B., Savitz , J., Nitta , M., España , L., Teague , T., Nelson , L., McCrea , M., & Meier , T. (2020). Systemic inflammation moderates the association of prior concussion with hippocampal volume and episodic memory in high school and collegiate athletes.
  • Dinga , R., Hahn , T., Eyler , L., Aftanas , L., Aghajani , M., Aleman , A., Baune , B., Berger , K., Brak , I., Filho , G., Carballedo , A., Connolly , C., Couvy-Duchesne , B., Cullen , K., Dannlowski , U., Davey , C., Dima , D., Enneking , V., Filimonova , E., Frenzel , S., Frodl , T., Godlewska , B., Gotlib , I., Grabe , H., Groenewold , N., Grotegerd , D., Gruber , O., Hall , G., Harrison , B., Hatton , S., Hermesdorf , M., Hickie , I., Ho , T., Hosten , N., Jansen , A., Kähler , C., Kircher , T., Klimes-Dougan , B., Krämer , B., Krug , A., Lagopoulos , J., Leenings , R., MacMaster , F., MacQueen , G., McIntosh , A., McLellan , Q., McMahon , K., Medland , S., Mueller , B., Mwangi , B., Osipov , E., Portella , M., Pozzi , E., Reneman , L., Repple , J., Sacchet , M., Sämann , P., Schnell , K., Schrantee , A., Simulionyte , E., Soares , J., Sommer , J., Stein , D., Steinsträter , O., Strike , L., Thomopoulos , S., van Tol , M., Veer , I., Walter , H., Whalley , H., Winter , N., Wittfeld , K., Wright , M., Wu , M., Völzke , H., Yang , T., Zannias , V., de Zubicaray , G., Zunta-Soares , G., Abé , C., Alda , M., Andreassen , O., Bøen , E., Bonnin , C., Canales-Rodriguez , E., Cannon , D., Caseras , X., Chaim-Avancini , T., Elvsåshagen , T., Favre , P., Foley , S., Fullerton , J., Goikolea , J., Hajek , T., Henry , C., Houenou , J., Howells , F., Ingvar , M., Kuplicki , R., Lafer , B., Landén , M., Machado-Vieira , R., Malt , U., McDonald , C., Mitchell , P., Nabulsi , L., Overs , B., Polosan , M., Pomarol-Clotet , E., Radua , J., Rive , M., Roberts , G., Ruhe , H., Salvador , R., Sarró , S., Satterthwaite , T., Savitz , J., Schene , A., Schofield , P., Serpa , M., Sim , K., Soeiro-de-Souza , M., Sutherland , A., Temmingh , H., Timmons , G., Uhlmann , A., Vieta , E., Wolf , D., Zanetti , M., Jahanshad , N., Thompson , P., Veltman , D., Marquand , A., Cole , J., & Schmaal , L. (2020). Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group.
  • Nitta , M., Savitz , J., Nelson , L., Teague , T., Hoelzle , J., McCrea , M., & Meier , T. (2019). Acute elevation of serum inflammatory markers predicts symptom recovery after concussion, 93, e497-e507.
  • Savitz , J. (2018). Musings on mania: A role for T-lymphocytes?, 73, 151-152.
  • First , M., Drevets , W., Carter , C., Dickstein , D., Kasoff , L., Kim , K., McConathy , J., Rauch , S., Saad , Z., Savitz , J., Seymour , K., Sheline , Y., & Zubieta , J. (2018). Clinical Applications of Neuroimaging in Psychiatric Disorders, 175, 915-916.
  • Savitz , J., & Harrison , N. (2018). Interoception and Inflammation in Psychiatric Disorders, 3, 514-524.
  • Savitz , J., Teague , T., Misaki , M., Macaluso , M., Wurfel , B., Meyer , M., Drevets , D., Yates , W., Gleason , O., Drevets , W., & Preskorn , S. (2018). Treatment of bipolar depression with minocycline and/or aspirin: an adaptive, 2×2 double-blind, randomized, placebo-controlled, phase IIA clinical trial, 8, 27.
  • Meier , T., Drevets , W., Teague , T., Wurfel , B., Mueller , S., Bodurka , J., Dantzer , R., & Savitz , J. (2018). Kynurenic acid is reduced in females and oral contraceptive users: Implications for depression, 67, 59-64.
  • Le , T., Savitz , J., Suzuki , H., Misaki , M., Teague , T., White , B., Marino , J., Wiley , G., Gaffney , P., & Drevets , W. (2018). Identification and replication of RNA-Seq gene network modules associated with depression severity, 8, 180.
  • Cho, H., Savitz, J., Dantzer, R., Teague, T., Drevets, W., & Irwin, M. (2017). Sleep disturbance and kynurenine metabolism in depression. Journal of Psychosomatic Research, 99, 1–7.

  • Suzuki, H., Savitz, J., Kent Teague, T., Gandhapudi, S., Tan, C., Misaki, M., … Bodurka, J. (2017). Altered populations of natural killer cells, cytotoxic T lymphocytes, and regulatory T cells in major depressive disorder: Association with sleep disturbance. Brain, Behavior, and Immunity.

  • He, H., Sui, J., Du , Y., Yu, Q., Lin, D., Drevets, W., … Calhoun, V. (2017). Co-altered functional networks and brain structure in unmedicated patients with bipolar and major depressive disorders. Brain Structure & Function.

  • Le , T., Kyle Simmons, W., Misaki, M., Bodurka, J., White, B., Savitz, J., & McKinney, B. (2017). Privacy preserving Evaporative Cooling feature selection and classification with Relief-F and Random Forests. Bioinformatics (Oxford, England).

  • Hibar, D., Westlye, L., Doan, N., Jahanshad, N., Cheung, J., Ching CRK, … Andreassen, O. (2017). Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group. Molecular Psychiatry.

  • Wurfel, B., Drevets, W., Bliss, S., McMillin, J., Suzuki, H., Ford, B., … Savitz, J. (2017). Serum kynurenic acid is reduced in affective psychosis. Translational Psychiatry, 7(5), e1115.

  • Meier, T., Lancaster, M., Mayer, A., Teague, T., & Savitz, J. (2017). Abnormalities in Functional Connectivity in Collegiate Football Athletes with and without a Concussion History: Implications and Role of Neuroactive Kynurenine Pathway Metabolites. Journal of Neurotrauma, 34(4), 824–837.

  • Victor, T., Drevets, W., Misaki, M., Bodurka, J., & Savitz, J. (2017). Sex differences in neural responses to subliminal sad and happy faces in healthy individuals: Implications for depression. Journal of Neuroscience Research, 95(1-2), 703–710.

  • Suzuki , H., Savitz , J., Teague , T., Gandhapudi , S., Tan , C., Misaki , M., McKinney , B., Irwin , M., Drevets , W., & Bodurka , J. (2017). Altered populations of natural killer cells, cytotoxic T lymphocytes, and regulatory T cells in major depressive disorder: association with sleep disturbance, 66, 193-200.
  • Le , T., Simmons , W., Misaki , M., Bodurka , J., White , B., Savitz , J., & McKinney , B. (2017). Differential privacy-based evaporative cooling feature selection and classification with relief-F and random forests, 33, 2906-2913.
  • Mechawar, N., & Savitz, J. (2016). Neuropathology of mood disorders: do we see the stigmata of inflammation? Translational Psychiatry, 6(11), e946.

  • Young, K., Drevets, W., Dantzer, R., Teague, T., Bodurka, J., & Savitz, J. (2016). Kynurenine pathway metabolites are associated with hippocampal activity during autobiographical memory recall in patients with depression. Brain, Behavior, and Immunity, 56, 335–42.

  • Meier, T., Savitz, J., Singh, R., Teague, T., & Bellgowan, P. (2016). Smaller Dentate Gyrus and CA2 and CA3 Volumes Are Associated with Kynurenine Metabolites in Collegiate Football Athletes. Journal of Neurotrauma, 33(14), 1349–57.

  • Singh, R., Savitz, J., Teague, T., Polanski, D., Mayer, A., Bellgowan, P., & Meier, T. (2016). Mood symptoms correlate with kynurenine pathway metabolites following sports-related concussion. Journal of Neurology, Neurosurgery, and Psychiatry, 87(6), 670–5.

  • Savitz, J. (2016). Role of Kynurenine Metabolism Pathway Activation in Major Depressive Disorders. Current Topics in Behavioral Neurosciences.

  • Meier, T., Drevets, W., Wurfel, B., Ford, B., Morris, H., Victor, T., … Savitz, J. (2016). Relationship between neurotoxic kynurenine metabolites and reductions in right medial prefrontal cortical thickness in major depressive disorder. Brain, Behavior, and Immunity, 53, 39–48.

  • Misaki, M., Suzuki, H., Savitz, J., Drevets, W., & Bodurka, J. (2016). Individual Variations in Nucleus Accumbens Responses Associated with Major Depressive Disorder Symptoms. Scientific Reports, 6, 21227.

  • He, H., Yu, Q., Du , Y., Vergara, V., Victor, T., Drevets, W., … Calhoun, V. (2016). Resting-state functional network connectivity in prefrontal regions differs between unmedicated patients with bipolar and major depressive disorders. Journal of Affective Disorders, 190, 483–93.

  • Misaki, M., Savitz, J., Zotev, V., Phillips, R., Yuan, H., Young, K., … Bodurka, J. (2015). Contrast enhancement by combining T1- and T2-weighted structural brain MR Images. Magnetic Resonance in Medicine, 74(6), 1609–20.

  • Savitz, J., Dantzer, R., Meier, T., Wurfel, B., Victor, T., McIntosh, S., … Drevets, W. (2015). Activation of the kynurenine pathway is associated with striatal volume in major depressive disorder. Psychoneuroendocrinology, 62, 54–8.

  • Savitz, J., Drevets, W., Wurfel, B., Ford, B., Bellgowan, P., Victor, T., … Dantzer, R. (2015). Reduction of kynurenic acid to quinolinic acid ratio in both the depressed and remitted phases of major depressive disorder. Brain, Behavior, and Immunity, 46, 55–9.

  • Savitz, J., Dantzer, R., Wurfel, B., Victor, T., Ford, B., Bodurka, J., … Drevets, W. (2015). Neuroprotective kynurenine metabolite indices are abnormally reduced and positively associated with hippocampal and amygdalar volume in bipolar disorder. Psychoneuroendocrinology, 52, 200–11.

  • Savitz , J., Drevets , W., Smith , C., Victor , T., Wurfel , B., Bellgowan , P., Bodurka , J., Teague , T., & Dantzer , R. (2015). Putative neuroprotective and neurotoxic kynurenine pathway metabolites are associated with hippocampal and amygdalar volumes in subjects with major depressive disorder, 40, 463-71.
  • Singh , R., Meier , T., Kuplicki , R., Savitz , J., Mukai , I., Cavanagh , L., Allen , T., Teague , T., Nerio , C., Polanski , D., & Bellgowan , P. (2014). Relationship of collegiate football experience and concussion with hippocampal volume and cognitive outcomes, 311, 1883-8.
  • Thompson , P., Stein , J., Medland , S., Hibar , D., Vasquez , A., Renteria , M., Toro , R., Jahanshad , N., Schumann , G., Franke , B., Wright , M., Martin , N., Agartz , I., Alda , M., Alhusaini , S., Almasy , L., Almeida , J., Alpert , K., Andreasen , N., Andreassen , O., Apostolova , L., Appel , K., Armstrong , N., Aribisala , B., Bastin , M., Bauer , M., Bearden , C., Bergmann , O., Binder , E., Blangero , J., Bockholt , H., Bøen , E., Bois , C., Boomsma , D., Booth , T., Bowman , I., Bralten , J., Brouwer , R., Brunner , H., Brohawn , D., Buckner , R., Buitelaar , J., Bulayeva , K., Bustillo , J., Calhoun , V., Cannon , D., Cantor , R., Carless , M., Caseras , X., Cavalleri , G., Chakravarty , M., Chang , K., Ching , C., Christoforou , A., Cichon , S., Clark , V., Conrod , P., Coppola , G., Crespo-Facorro , B., Curran , J., Czisch , M., Deary , I., de Geus , E., den Braber , A., Delvecchio , G., Depondt , C., de Haan , L., de Zubicaray , G., Dima , D., Dimitrova , R., Djurovic , S., Dong , H., Donohoe , G., Duggirala , R., Dyer , T., Ehrlich , S., Ekman , C., Elvsåshagen , T., Emsell , L., Erk , S., Espeseth , T., Fagerness , J., Fears , S., Fedko , I., Fernández , G., Fisher , S., Foroud , T., Fox , P., Francks , C., Frangou , S., Frey , E., Frodl , T., Frouin , V., Garavan , H., Giddaluru , S., Glahn , D., Godlewska , B., Goldstein , R., Gollub , R., Grabe , H., Grimm , O., Gruber , O., Guadalupe , T., Gur , R., Gur , R., Göring , H., Hagenaars , S., Hajek , T., Hall , G., Hall , D., Hardy , J., Hartman , C., Hass , J., Hatton , S., Haukvik , U., Hegenscheid , K., Heinz , A., Hickie , I., Ho , B., Hoehn , D., Hoekstra , P., Hollinshead , M., Holmes , A., Homuth , G., Hoogman , M., Hong , L., Hosten , N., Hottenga , J., Hulshoff Pol , H., Hwang , K., Jack, Jr , C., Jenkinson , M., Johnston , C., Jönsson , E., Kahn , R., Kasperaviciute , D., Kelly , S., Kim , S., Kochunov , P., Koenders , L., Krämer , B., Kwok , J., Lagopoulos , J., Laje , G., Landen , M., Landman , B., Lauriello , J., Lawrie , S., Lee , P., Le Hellard , S., Lemaître , H., Leonardo , C., Li , C., Liberg , B., Liewald , D., Liu , X., Lopez , L., Loth , E., Lourdusamy , A., Luciano , M., Macciardi , F., Machielsen , M., Macqueen , G., Malt , U., Mandl , R., Manoach , D., Martinot , J., Matarin , M., Mather , K., Mattheisen , M., Mattingsdal , M., Meyer-Lindenberg , A., McDonald , C., McIntosh , A., McMahon , F., McMahon , K., Meisenzahl , E., Melle , I., Milaneschi , Y., Mohnke , S., Montgomery , G., Morris , D., Moses , E., Mueller , B., Muñoz Maniega , S., Mühleisen , T., Müller-Myhsok , B., Mwangi , B., Nauck , M., Nho , K., Nichols , T., Nilsson , L., Nugent , A., Nyberg , L., Olvera , R., Oosterlaan , J., Ophoff , R., Pandolfo , M., Papalampropoulou-Tsiridou , M., Papmeyer , M., Paus , T., Pausova , Z., Pearlson , G., Penninx , B., Peterson , C., Pfennig , A., Phillips , M., Pike , G., Poline , J., Potkin , S., Pütz , B., Ramasamy , A., Rasmussen , J., Rietschel , M., Rijpkema , M., Risacher , S., Roffman , J., Roiz-Santiañez , R., Romanczuk-Seiferth , N., Rose , E., Royle , N., Rujescu , D., Ryten , M., Sachdev , P., Salami , A., Satterthwaite , T., Savitz , J., Saykin , A., Scanlon , C., Schmaal , L., Schnack , H., Schork , A., Schulz , S., Schür , R., Seidman , L., Shen , L., Shoemaker , J., Simmons , A., Sisodiya , S., Smith , C., Smoller , J., Soares , J., Sponheim , S., Sprooten , E., Starr , J., Steen , V., Strakowski , S., Strike , L., Sussmann , J., Sämann , P., Teumer , A., Toga , A., Tordesillas-Gutierrez , D., Trabzuni , D., Trost , S., Turner , J., Van den Heuvel , M., van der Wee , N., van Eijk , K., van Erp , T., van Haren , N., van ’t Ent , D., van Tol , M., Valdés Hernández , M., Veltman , D., Versace , A., Völzke , H., Walter , H., Wang , L., Wardlaw , J., Weale , M., Weiner , M., Wen , W., Westlye , L., Whalley , H., Whelan , C., White , T., Winkler , A., Wittfeld , K., Woldehawariat , G., Wolf , C., Zilles , D., Zwiers , M., Thalamuthu , A., Schofield , P., Freimer , N., Lawrence , N., & Drevets , W. (2014). The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data, 8, 153-82.
  • Relationship of collegiate football experience and concussion with hippocampal volume and cognitive outcomes. (2014), 311, 1883-8.
  • Savitz , J., Price , J., & Drevets , W. (2014). Neuropathological and neuromorphometric abnormalities in bipolar disorder: view from the medial prefrontal cortical network, 42, 132-47.
  • Savitz , J., Rauch , S., & Drevets , W. (2013). Reproduced from Habenula volume in bipolar disorder and major depressive disorder: a high-resolution magnetic resonance imaging study, 18, 523.
  • Savitz , J., Hodgkinson , C., Martin-Soelch , C., Shen , P., Szczepanik , J., Nugent , A., Herscovitch , P., Grace , A., Goldman , D., & Drevets , W. (2013). DRD2/ANKK1 Taq1A polymorphism (rs1800497) has opposing effects on D2/3 receptor binding in healthy controls and patients with major depressive disorder, 16, 2095-101.
  • Savitz , J., Rauch , S., & Drevets , W. (2013). Clinical application of brain imaging for the diagnosis of mood disorders: the current state of play, 18, 528-39.
  • Savitz , J., & Drevets , W. (2013). Neuroreceptor imaging in depression, 52, 49-65.
  • Savitz , J., Nugent , A., Bellgowan , P., Wright , N., Tinsley , R., Zarate, Jr , C., Herscovitch , P., & Drevets , W. (2013). Catecholamine depletion in first-degree relatives of individuals with mood disorders: An [(18)F]fluorodeoxyglucose positron emission tomography study, 2, 341-55.
  • Savitz , J., Hodgkinson , C., Martin-Soelch , C., Shen , P., Szczepanik , J., Nugent , A., Herscovitch , P., Grace , A., Goldman , D., & Drevets , W. (2013). The functional DRD3 Ser9Gly polymorphism (rs6280) is pleiotropic, affecting reward as well as movement, 8, e54108.
  • Savitz , J., Frank , M., Victor , T., Bebak , M., Marino , J., Bellgowan , P., McKinney , B., Bodurka , J., Teague , T., & Drevets , W. (2013). Inflammation and neurological disease-related genes are differentially expressed in depressed patients with mood disorders and correlate with morphometric and functional imaging abnormalities, 31, 161-171.
  • Pandey , A., Davis , N., White , B., Pajewski , N., Savitz , J., Drevets , W., & McKinney , B. (2012). Epistasis network centrality analysis yields pathway replication across two GWAS cohorts for bipolar disorder, 2, e154.
  • Savitz , J., Frank , M., Victor , T., Bebak , M., Marino , J., Bellgowan , P., McKinney , B., Bodurka , J., Kent , T., & Drevets , W. (2012). Inflammation and neurological disease-related genes are differentially expressed in depressed patients with mood disorders and correlate with morphometric and functional imaging abnormalities, S0889-1591, 00469-2.
  • Identification of common variants associated with human hippocampal and intracranial volumes. (2012), 44, 552-61.
  • Savitz , J., Preskorn , S., Teague , T., Drevets , D., Yates , W., & Drevets , W. (2012). Minocycline and aspirin in the treatment of bipolar depression: a protocol for a proof-of-concept, randomised, double-blind, placebo-controlled, 2×2 clinical trial, 2, e000643.
  • Savitz , J., Nugent , A., Cannon , D., Carlson , P., Davis , R., Neumeister , A., Rallis-Frutos , D., Fromm , S., Herscovitch , P., & Drevets , W. (2012). Effects of arterial cannulation stress on regional cerebral blood flow in major depressive disorder, 2, 308.
  • Savitz , J., Frank , B., McKinney , B., Teague , T., & Drevets , W. (2012). 45. Increased PBMC expression of inflammation and neurological disease-associated genes correlates with anhedonia, the BOLD response to masked happy faces and subgenual anterior cingulate cortex volume in patients with primary mood disorders, 26, S13.
  • Pandey , A., Davis , N., White , B., Pajewski , N., Savitz , J., Drevets , W., & McKinney , B. (2012). Epistasis network centrality analysis yields pathway replication across two GWAS cohorts for bipolar disorder, 2, e154.
  • Savitz , J., Bonne , O., Nugent , A., Vythilingam , M., Bogers , W., Charney , D., & Drevets , W. (2011). Habenula volume in post-traumatic stress disorder measured with high-resolution MRI, 1, 7.
  • Cannon , D., Klaver , J., Gandhi , S., Solorio , G., Peck , S., Erickson , K., Akula , N., Savitz , J., Eckelman , W., Furey , M., Sahakian , B., McMahon , F., & Drevets , W. (2011). Genetic variation in cholinergic muscarinic-2 receptor gene modulates M2 receptor binding in vivo and accounts for reduced binding in bipolar disorder, 16, 407-18.
  • Savitz , J., Nugent , A., Bogers , W., Roiser , J., Bain , E., Neumeister , A., Zarate, Jr , C., Manji , H., Cannon , D., Marrett , S., Henn , F., Charney , D., & Drevets , W. (2011). Habenula volume in bipolar disorder and major depressive disorder: a high-resolution magnetic resonance imaging study, 69, 336-43.
  • Savitz , J., & Drevets , W. (2011). Neuroimaging and neuropathological findings in bipolar disorder, 5, 201-25.
  • Savitz , J., van der Merwe , L., Newman , T., Stein , D., & Ramesar , R. (2010). Catechol-o-methyltransferase genotype and childhood trauma may interact to impact schizotypal personality traits, 40, 415-23.
  • Savitz , J., Nugent , A., Bogers , W., Liu , A., Sills , R., Luckenbaugh , D., Bain , E., Price , J., Zarate , C., Manji , H., Cannon , D., Marrett , S., Charney , D., & Drevets , W. (2010). Amygdala volume in depressed patients with bipolar disorder assessed using high resolution 3T MRI: the impact of medication, 49, 2966-76.
  • Savitz , J., & Drevets , W. (2009). Imaging phenotypes of major depressive disorder: genetic correlates, 164, 300-30.
  • Savitz , J., Lucki , I., & Drevets , W. (2009). 5-HT(1A) receptor function in major depressive disorder, 88, 17-31.
  • Savitz , J., & Drevets , W. (2009). Bipolar and major depressive disorder: neuroimaging the developmental-degenerative divide, 33, 699-771.
  • Stein , D., Horn , N., Ramesar , R., & Savitz , J. (2009). Bipolar disorder: emotional dysregulation and neuronal vulnerability, 14, 122-6.
  • Savitz , J., van der Merwe , L., Stein , D., Solms , M., & Ramesar , R. (2009). Neuropsychological status of bipolar I disorder: impact of psychosis, 194, 243-51.
  • Stein , D., Daniels , W., Savitz , J., & Harvey , B. (2008). Brain-derived neurotrophic factor: the neurotrophin hypothesis of psychopathology, 13, 945-9.
  • Savitz , J., van der Merwe , L., & Ramesar , R. (2008). Personality endophenotypes for bipolar affective disorder: a family-based genetic association analysis, 7, 869-76.
  • Savitz , J., van der Merwe , L., & Ramesar , R. (2008). Hypomanic, cyclothymic and hostile personality traits in bipolar spectrum illness: a family-based study, 42, 920-9.
  • Savitz , J., van der Merwe , L., & Ramesar , R. (2008). Dysthymic and anxiety-related personality traits in bipolar spectrum illness, 109, 305-11.
  • Drevets , W., Savitz , J., & Trimble , M. (2008). The subgenual anterior cingulate cortex in mood disorders, 13, 663-81.
  • Savitz , J., van der Merwe , L., Stein , D., Solms , M., & Ramesar , R. (2008). Neuropsychological task performance in bipolar spectrum illness: genetics, alcohol abuse, medication and childhood trauma, 10, 479-94.
  • Savitz , J., van der Merwe , L., Newman , T., Solms , M., Stein , D., & Ramesar , R. (2008). The relationship between childhood abuse and dissociation. Is it influenced by catechol-O-methyltransferase (COMT) activity?, 11, 149-61.
  • Savitz , J., van der Merwe , L., Solms , M., & Ramesar , R. (2007). Lateralization of hand skill in bipolar affective disorder, 6, 698-705.
  • Savitz , J., van der Merwe , L., Stein , D., Solms , M., & Ramesar , R. (2007). Genotype and childhood sexual trauma moderate neurocognitive performance: a possible role for brain-derived neurotrophic factor and apolipoprotein E variants, 62, 391-9.
  • Savitz , J., Cupido , C., & Ramesar , R. (2007). Preliminary evidence for linkage to chromosome 1q31-32, 10q23.3, and 16p13.3 in a South African cohort with bipolar disorder, 144B, 383-7.
  • Savitz , J., van der Merwe , L., Solms , M., & Ramesar , R. (2007). Neurocognitive function in an extended Afrikaner-ancestry family with affective illness, 32, 116-20.
  • Savitz , J., van der Merwe , L., Solms , M., & Ramesar , R. (2007). A linkage and family-based association analysis of a potential neurocognitive endophenotype of bipolar disorder, 9, 101-16.
  • Stein , D., Newman , T., Savitz , J., & Ramesar , R. (2006). Warriors versus worriers: the role of COMT gene variants, 11, 745-8.
  • Savitz , J., & Ramesar , R. (2006). Personality: is it a viable endophenotype for genetic studies of bipolar affective disorder?, 8, 322-37.
  • Savitz , J., Solms , M., & Ramesar , R. (2006). Apolipoprotein E variants and cognition in healthy individuals: a critical opinion, 51, 125-35.
  • Savitz , J., Solms , M., & Ramesar , R. (2006). The molecular genetics of cognition: dopamine, COMT and BDNF, 5, 311-28.
  • Savitz , J., Cupido , C., & Ramesar , R. (2006). Trends in suicidology: personality as an endophenotype for molecular genetic investigations, 3, e107.
  • Savitz , J., Solms , M., & Ramesar , R. (2005). Neuropsychological dysfunction in bipolar affective disorder: a critical opinion, 7, 216-35.
  • Savitz , J., Solms , M., & Ramesar , R. (2005). Neurocognitive function as an endophenotype for genetic studies of bipolar affective disorder, 7, 275-86.
  • Savitz , J., Solms , M., Pietersen , E., Ramesar , R., & Flor-Henry , P. (2004). Dissociative identity disorder associated with mania and change in handedness, 17, 233-7.
  • Savitz , J., & Ramesar , R. (2004). Genetic variants implicated in personality: a review of the more promising candidates, 131B, 20-32.
  • Savitz , J., & Jansen , P. (2003). The stroop color-word interference test as an indicator of ADHD in poor readers, 164, 319-33.

Courses Taught

  • Dissertation Research
  • Research Experience

Professional Affiliations

  • American College of Neuropsychopharmacology
  • Psychoneuroimmunology Research Society

Awards & Honors

  • Faculty of Health Sciences Nominee for The University of Tulsa Research Award
  • Awardee of the Career Development Institute for Bipolar Disorder, Univ. of Pittsburgh
  • University of the Witwatersrand Postgraduate Merit Scholarship
  • University of the Witwatersrand Council Merit Scholarship
  • UCT Research Associateship
  • Witwatersrand University Postgraduate Merit Bursary
  • Centre for Science Development Scholarship
  • Post-Doctoral Fellow, Brain and Behaviour Initiative
  • South African Medical Research Council Local Scholarship
  • NARSAD Anita C. and Robert F. Mitchell Memorial Investigator
  • Post-Doctoral Fellow
  • NARSAD Young Investigator Award
  • ACNP Associate Member
  • Career Development Award