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William Potter, PhD

William Potter, PhD
Professor of Chemistry
College of Engineering & Natural Sciences
Chemistry and Biochemistry
918-631-3027 Keplinger Hall Room 2225

Education

PhD – Colorado State University Other – Bonthe Secondary School BS – University of Notre Dame

Bio

William Potter's research interests involve the development of non-invasive diagnostics. Presently, he is working on a joint project with the Psychology Department to determine biochemical markers which correlate to an individual's personality. The research is focused on the individual's susceptibility to stress and their fear response. They are studying the specific genetic and bio-markers that are related to the hypothalamus-pituitary-adrenal axis (HPA axis). Theses markers are collected from exhaled breath condensate, non-stimulate saliva and buccal swabs and include cortisol, SLC6A4, COMT, MAO-A, BDNF and CRH receptor genetics and other more novel saliometric parameters. This research is connected with ongoing research on post-traumatic stress in rape and abuse victims in collaboration with the TITAN Institute and with pain research that is trying to evaluate the factors responsible for each individual's sensitivity to pain. Their collaborative work is an extension of previous studies on the development of non-invasive diagnostics using high resolution laser spectroscopy (TDLAS). These studies focused on the evaluation of oxidative stress, cancer biomarkers and environmental pollutants. The breath exhalation studies included diagnostic molecules such as nitric oxide and formaldehyde.

Research Interests

Steroid Hormones and Metabolic Products with respect to Mental Health
Effects of Exercise and other Treatment Regimes
Non-invasive Salivary and Hair Diagnostics

Teaching Interests

Biochemistry
Clinical Biochemistry
Biochemistry of Nutrition
Biochemistry of Nutraceuticals

Publications

  • Potter, W.T., et al., Direct measurement of carbon monoxide bound to different subunits of hemoglobin A in solution and in red cells by infrared spectroscopy. Biochemical and Biophysical Research Communications, 1983. 116(2): p. 719-725.

  • Potter, W.T., R.A. Houtchens, and W.S. Caughey, Crystallization-induced changes in protein structure observed by infrared spectroscopy of carbon monoxide liganded to human hemoglobins A and Zurich. Journal of the American Chemical Society, 1985. 107(11): p. 3350-3352.

  • Potter, W.T., et al., Effects of protein structure on dioxygen stretch bands in infrared spectra of oxyhemoglobins and oxymyoglobins. Federation Proceedings, 1985. 44(5).

  • Potter, W.T., et al., Infrared spectra of carbonyl hemoglobins: Characterization of dynamic heme pocket conformers. Biochemistry, 1990. 29(26): p. 6283-6295.

  • Potter, W.T., Ligand infrared spectra of hemoglobins and myoglobins: implications re protein structure and function. 1986. p. 216 pp.

  • Potter, W.T., et al., Radiometric assay of red cell and plasma cholinesterase in pesticide appliers from Minnesota. Toxicol. Appl. Pharmacol., 1993. 119(1): p. 150-5.

  • Iacoe, D.W., W.T. Potter, and D. Teeters, Simple generation of C60 (buckminsterfullerene): a process suitable for undergraduate research laboratories. J. Chem. Educ., 1992. 69(8): p. 663.

  • Potter, W.T., et al., Phosphine-mediated Heinz body formation and hemoglobin oxidation in human erythrocytes. Toxicology Letters, 1991. 57(1): p. 37-45.

  • Potter, W.T., J. Cho, and K.L. Sublette, Reduction of nitric oxide to nitrous oxide by cobalt porphyrins and corrins. Fuel Process. Technol., 1994. 40(2+3): p. 355-60.

  • Potter, W. T.; Cho, J. G.; and Sublette, K. L., “Reduction of Nitric Oxide to Nitrous Oxide Monitored by Fourier Transform Infrared Spectroscopy,” Fuel Processing Technology, 40, 355-360 (1994).

  • Cho, J.G., W.T. Potter, and K.L. Sublette, Porphyrin-catalyzed reduction of nitroaromatics for the treatment of pink water. Appl. Biochem. Biotechnol., 1994. 45-46: p. 861-70.

  • Cho, Jeong-Guk; Potter, William T.; and Sublette, Kerry L., “Porphyrin-Catalyzed Reduction of Nitroaromatics for Treatment of Pink Water”, Applied Biochemistry and Biotechnology, 45/46, 861-870 (1994).

  • Potter, W.T., et al., Biomimetic and microbial reduction of nitric oxide. Appl Biochem Biotechnol, 1995. 51-52(1): p. 771-784.

  • Duncan, K., et al., Nitrogen cycling and nitric oxide emissions in oil-impacted prairie soils. Biorem. J., 1997. 1(3): p. 195-208.

  • Duncan, K., Kolhatkar, R., Subramanian, G., Narasimhan, R., Jennings, E., Hettenbach, S., Brown, A., McComas, C., Potter, W.T., and Sublette, K.L, “Microbial Dynamics of Oil-Impacted Prairie Soil”, Applied Biochemistry and Biotechnology, 77-79, 421-434 (1999).

  • Duncan, K.E., et al., Microbial dynamics in oil-impacted prairie soil. Appl. Biochem. Biotechnol., 1999. 77-79(Twentieth Symposium on Biotechnology for Fuels and Chemicals, 1998): p. 421-434.

  • Stann, B., et al. Line imaging ladar using a laser diode transmitter and FM/cw radar principles for submunition applications. in Proceedings of SPIE – The International Society for Optical Engineering. 2000.

  • Narasimhan, R., et al., Ozone modeling using neural networks. Journal of Applied Meteorology, 2000. 39(3): p. 291-296.

  • Roller, C., et al., Simultaneous NO and CO2 measurement in human breath with a single IV-VI mid-infrared laser. Optics Letters, 2002. 27(2): p. 107-109.

  • Wert, B.P., et al., Signatures of terminal alkene oxidation in airbone formaldehyde measurements during TexAQS 2000. Journal of Geophysical Research D: Atmospheres, 2003. 108(3): p. ACH 8-1 – ACH 8-14.

  • Fried, A., et al., Airborne tunable diode laser measurements of formaldehyde during TRACE-P: Distributions and box model comparisons. Journal of Geophysical Research D: Atmospheres, 2003. 108(20): p. GTE 19-1 – 19-23.

  • Ryerson, T.B., et al., Effect of petrochemical industrial emissions of reactive alkenes and NOx on tropospheric ozone formation in Houston, Texas. Journal of Geophysical Research D: Atmospheres, 2003. 108(8): p. ACH 8-1 – ACH 8-24.

  • Duncan, K., et al., Multi-species ecotoxicity assessment of petroleum-contaminated soil. Soil Sediment Contam., 2003. 12(2): p. 181-206.

  • Ruff, W., et al., Translational doppler detection using direct-detect chirped amplitude-modulated laser radar. Microwave and Optical Technology Letters, 2004. 43(4): p. 358-363.

  • Williams, D.J., et al., The impact of background ozone on compliance with revised National Ambient Air Quality Standards. Journal of the Air and Waste Management Association, 2009. 59(1): p. 52-57.

  • Caruso, J.F., et al., Blood lactate and hormonal responses to prototype flywheel ergometer workouts. Journal of Strength and Conditioning Research, 2010. 24(3): p. 749-756.

  • Palit, S.,** Sheaff, R. J., France, C. R., McGlone, S., Potter, W., Harkness, A., McNulty, J., Bartley, E. J.,* Hoffman, R., Monda, J. K., & Rhudy, J. L. (2011). Serotonin transporter gene (5-HTTLPR) polymorphisms are associated with emotional modulation of pain but not emotional modulation of spinal nociception. Biological Psychology, 86, 360-369. PMID: 21291949

  • Caruso, J., et al., Ergogenic effects of β-alanine and carnosine: proposed future research to quantify their efficacy. Nutrients, 2012. 4: p. 585-601.

  • Caruso, J.F., et al., Salivary hormonal values from high-speed resistive exercise workouts. Journal of Strength and Conditioning Research, 2012. 26(3): p. 625-632.

  • Palit S, Sheaff RJ, France CR, McGlone S, Potter WT, Harkness A, McNulty J, Bartley EJ, Hoffmann R, Monda JK, Rhudy JL. Serotonin Transporter Gene (SLC6A4) Polymorphisms and Emotional Modulation of Pain and Nociception. Biological Psychology 86 (2011) 360–369.

  • Caruso, J., et al., b-Alanine’s impact on exercise and blood lactate values incurred from repetitive supramaximal activity, Isokinetics and Exercise Science, 2014. 22(1): 303-309.

  • Caruso J.F., U.M.A., Giebel R.M., Barbosa A.G., Craig C.E., Mason M.L., Unruh K.D., Borgsmiller J.A., and Potter W.T., Human testosterone and lactate responses to flywheel ergometry exercise: effect of contractile mode and work volume. Gravitational and Space Research, 2014. 2(1): p. 108-116.

  • Caruso, J.F., et al., Lactate, cortisol and testosterone values from high-speed resistive exercise workouts done by women. Isokinetics and Exercise Science, 2014. 22(1): p. 9-16.

  • Khosrow, N., et al., Exhaled nitric oxide measured using mid-infrared spectroscopy. SAE Technical Papers, 2002.

  • Duffy, L., et al., Treatment of newborns with persistent pulmonary hypertension using inhalational nitric oxide therapy. Book of Abstracts, 211th ACS National Meeting, New Orleans, LA, March 24-28, 1996: p. CHED-251.

  • Norman, D.L., et al., Influence of ammonium doping in cigarets and nitric oxide (NO) levels upon combustion. Book of Abstracts, 211th ACS National Meeting, New Orleans, LA, March 24-28, 1996: p. CHED-228.

  • Croley, B., et al., Evaluation of tropospheric ozone levels using neural network modeling. Book of Abstracts, 215th ACS National Meeting, Dallas, March 29-April 2, 1998: p. CHED-251.

  • Teeters, D., W.A. Redman, and W.T. Potter, Surface characterization of surfactant-modified non-impact inks. Book of Abstracts, 215th ACS National Meeting, Dallas, March 29-April 2, 1998: p. I&EC-082.

  • Croley, B., E. Raasch, and W.T. Potter, Neural models for ozone air quality evaluation. Book of Abstracts, 217th ACS National Meeting, Anaheim, Calif., March 21-25, 1999: p. CHED-589.

  • Raasch, E.W., et al., Implementation of mid-IR tunable diode laser spectrometers in metabolic monitoring. Book of Abstracts, 219th ACS National Meeting, San Francisco, CA, March 26-30, 2000, 2000: p. CHED-591.

  • Namjou, K., P.J. McCann, and W.T. Potter. Breath testing with a mid-IR laser spectrometer. in Proceedings of SPIE – The International Society for Optical Engineering. 1999.

  • Croley, B. and W.T. Potter, Multiple-year analyses of the influence of NOx on Tulsa area tropospheric ozone. Book of Abstracts, 219th ACS National Meeting, San Francisco, CA, March 26-30, 2000, 2000: p. CHED-229.

  • Burn, A.K., et al., Implementation of tunable diode laser spectroscopy for non-invasive breath diagnostics. Abstracts of Papers, 221st ACS National Meeting, San Diego, CA, United States, April 1-5, 2001, 2001: p. CHED-602.

  • Stann, B., et al. Research progress on scannerless ladar systems using a laser diode transmitter and FM/cw radar principles. in Proceedings of SPIE – The International Society for Optical Engineering. 2001.

  • Potter, W.T., et al., High-resolution spectroscopy using tunable diode lasers for noninvasive breath diagnostics. Book of Abstracts, 219th ACS National Meeting, San Francisco, CA, March 26-30, 2000, 2000: p. CHED-588.

  • McConnell, D.L., et al., Impact of bioaerosals and outdoor pollutants on pulmonary function. Abstracts of Papers, 221st ACS National Meeting, San Diego, CA, United States, April 1-5, 2001, 2001: p. CHED-601.

  • Colbert, N., et al., Formaldehyde detection in Asian outflow with tunable diode laser spectroscopy. Abstracts of Papers, 223rd ACS National Meeting, Orlando, FL, United States, April 7-11, 2002, 2002: p. CHED-457.

  • Stephenson, B., W.T. Potter, and J. Hall, Development of a biocompatible polymer scaffold for tissue engineering. Abstracts of Papers, 227th ACS National Meeting, Anaheim, CA, United States, March 28-April 1, 2004, 2004: p. CHED-165.

  • Iski, E., T. Harris, and W.T. Potter, Evaluation of chloride content in automotive catalytic converters. Abstracts of Papers, 229th ACS National Meeting, San Diego, CA, United States, March 13-17, 2005, 2005: p. CHED-316.

  • Libby, A.E. and W.T. Potter, Manganese detection in breath condensates. Abstracts of Papers, 229th ACS National Meeting, San Diego, CA, United States, March 13-17, 2005, 2005: p. CHED-1141.

  • Moskal, M., et al., Bioremediation of mining refuse at Tar Creek. Abstracts of Papers, 229th ACS National Meeting, San Diego, CA, United States, March 13-17, 2005, 2005: p. CHED-951.

  • Williamson, K., W.T. Potter and R.E. Howard, Computer siulated molecular binding of anti-cancer drugs to C-KIT Tyrosine Kinase, 229th ACS National Meeting, San Diego, CA, March 13-17, 2005: CHED-687.

  • Santoro, M.A., et al., Brain-derived neurotrophic factor role in stress response. Abstracts of Papers, 237th ACS National Meeting, Salt Lake City, UT, United States, March 22-26, 2009, 2009: p. CHED-296.

  • Palit, S. **, Hoffmann, R., Monda, J. K., DelVentura, J. L. *, Bartley, E. J. *, Sheaff, R. J., Potter, W., France, C. R., Harkness, A., McNulty, J., & Rhudy, J. L. (2009). Do 5-HT Transporter Gene (SLC6A4) Polymorphisms Confer Risk for Situation-Specific Pain Catastrophizing?: A Pilot Study. Program No. 779.2. Neuroscience Meeting Planner. Chicago, IL: Society for Neuroscience, 2009. Online.

  • Hughes, R.C., et al., Understanding genetic characteristics of the human stress response. Abstracts of Papers, 237th ACS National Meeting, Salt Lake City, UT, United States, March 22-26, 2009, 2009: p. CHED-430

  • Monda, J.K., et al., Analysis of metal content in multidrug resistant cancer cells by ICP-MS. Abstracts of Papers, 237th ACS National Meeting, Salt Lake City, UT, United States, March 22-26, 2009, 2009: p. CHED-286.

  • Palit, S.**, Hoffmann, R., Sheaff, R. J., McGlone, S., France, C. R., Potter, W., Harkness, A., McNulty, J., Bartley, E. J. *, Monda, J. K., & Rhudy, J. L.. Associations between serotonin transporter gene (SLC6A4) polymorphisms and emotional modulation of pain and nociception. Program No. 487.1/XX13. 2010 Neuroscience Meeting Planner, San Diego, CA: Society for Neuroscience, 2010. Online.

  • Quick, B., et al., Gene markers in post-traumatic stress disorder. Abstracts of Papers, 239th ACS National Meeting, San Francisco, CA, United States, March 21-25, 2010, 2010: p. CHED-539.

  • “Modification of Inks and Toners for Enhanced Deinking and Separation,” (co-authored with William Potter) Final report for the Center for Resource Conservation and Environmental Research, Oklahoma Alliance for Public Policy Research, 1995.

Courses Taught

  • Introduction to Research
  • Neurochemistry
  • Senior Seminar I
  • Undergraduate Research
  • Environmental Chemistry