Syed Hussaini PhD

Associate Professor of Chemistry and Biochemistry College of Engineering & Natural Sciences
Chemistry and Biochemistry
Curriculum Vitae [PDF]


Syed Raziullah Hussaini was born in Karachi, Pakistan. He goes by his middle name, Razi. He received his B.Sc. with honors in 1995 and M.Sc. in Organic Chemistry from the University of Karachi, Pakistan in 1996. After a short stint at Eli Lilly-Gohar(Pvt.) Ltd., he joined the HEJ Research Institute of Chemistry, Pakistan 1997. In 2000, he recived the Lady Noon/OUP scholarship which allowed him to carry out his DPhil at the University of Oxford. The Department of Chemistry and St. Peter's College at Oxford provided him with the bursaries to meet the university and the college fees respectively. In Oxford, Razi joined Dr. Mark Moloney's group in 2001 and finished his DPhil studies in 2004. Afterward, he moved across the Atlantic to work with Dr. Robert B. Grossman at the University of Kentucky. In 2005, he moved to Emory University and worked as a postdoc with Dr. Simon Blakey. In 2006, he moved back to the University of Kentucky and carried out his postdoctoral work with Dr. Peter Crooks. There, he also started teaching in the Department of Chemistry as a part-time instructor. From 2007-2009, Dr. Hussaini worked at the University of Louisville teaching various undergraduate and graduate level chemistry courses. During this period, he also conducted research with Dr. G. B. Hammond. In 2009, he accepted his current position at The University of Tulsa. He is interested in the synthesis of bioactive compounds.  Currently, the following projects are under investigation: 1. Development of new methods for the synthesis of enaminones. 2. Enantioselective synthesis of anti-smoking agents.

Ph.D., Oxford University
M.S., University of Karachi
B.S., University of Karachi

Development of Selective C-C Bond Forming Methods
Domino Reactions
Synthesis of Bioactive Compounds

Organic Chemistry
Physical Organic Chemistry
Synthetic Organic Chemistry

The following may be selected publications rather than a comprehensive list.

Journal Articles

Pal, Arpal et al. “Copper-Catalyzed Chemoselective Cross-Coupling Reaction of Thioamides and α-Diazocarbonyl Compounds: Synthesis of Enaminones.” Tetrahedron Letters 58.6 (2017): 586–589. Print.

Pal, Arpan et al. “Corrigendum to ‘Copper-Catalyzed Chemoselective Cross-Coupling Reaction of Thioamides and α-Diazocarbonyl Compounds: Synthesis of Enaminones’ [Tetrahedron Lett. 58 (2017) 586–589].” Tetrahedron Letters 58.9 (2017): 902 -. Print.

Hussaini, Syed, Raghu Chamala, and Zhiguo Wang. “The Eschenmoser Sulfide Contraction Method and Its Application in the Synthesis of Natural Products .” Tetrahedron 71.36 (2015): 6017–6086. Print.

Elliott, M et al. “Identification of Novel Proteasome Inhibitors from an Enaminone Library.” Chemical biology & drug design (2014): n. pag. Print.

Koduri, N et al. “Enaminones via Ruthenium-Catalyzed Coupling of Thioamides and α-Diazocarbonyl Compounds.” The Journal of organic chemistry 79.16 (2014): 7405–14. Print.

Hussaini, Syed. “Converting Chair-like Transition States into Zig-Zag Projections.” Resonance 19.9 (2014): 846–850. Print.

Koduri, Naga et al. “Acceleration of the Eschenmoser Coupling Reaction by Sonication: Efficient Synthesis of Enaminones.” RSC Adv. 3.1 (2013): 181–188. Print.

Koduri, N et al. “Ruthenium Catalyzed Synthesis of Enaminones.” Organic letters 14.2 (2012): 440–3. Print.

Hussaini, Syed. “Method for the Drawing of Newman Projections: Understanding Newman Projections with the Help of Hands.” Resonance 17.3 (2012): 291–294. Print.

Kimura, Y. et al. “Synthesis of Stacked-Cup Carbon Nanotubes in a Metal Free Low Temperature System.” Nanoscience and Nanotechnology Letters 3.1 (2011): 4–10. Print.

Hussaini, Syed. “Interconversion of Fischer and Zig-Zag Projections Learning Stereochemistry with the Help of Hands.” Resonance 15.4 (2010): 351–354. Print.

Hussaini, Syed, and G.B. Hammond. “Eschenmoser Coupling Reaction of Selenoamides. Synthesis of Enamino Ester.” Arkivoc 2008.13 (2008): 129–136. Print.

Hussaini, Syed, and M Moloney. “2,5-Disubstituted Pyrrolidines: Synthesis by Enamine Reduction and Subsequent Regioselective and Diastereoselective Alkylations.” Organic & biomolecular chemistry 4.13 (2006): 2600–15. Print.

Faulkner, J et al. “On the Sequence of Bond Formation in Loline Alkaloid Biosynthesis.” Chembiochem : a European journal of chemical biology 7.7 (2006): 1078–88. Print.

Hussaini, Syed, and M.G. Moloney. “Regioselective Reduction of β-Enaminoesters.” Synthetic Communications 35.8 (2005): 1129–1134. Print.

Hussaini, Syed, and Mark Moloney. “Cis-Selective Synthesis of 2,5-Disubstituted Pyrrolidines .” Tetrahedron Letters 45.6 (2004): 1125–1127. Print.

Hussaini, Syed, and M Moloney. “2,5-Disubstituted Pyrrolidines: Versatile Regioselective and Diastereoselective Synthesis by Enamine Reduction and Subsequent Alkylation.” Organic & biomolecular chemistry 1.11 (2003): 1838–41. Print.

Conference Proceedings

Schmauch, Marissa et al. “Macromonomer Synthesis towards Improving the Healing Efficiency of a Self-Healing Epoxy Matrix.” ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. Vol. 251. 2016. Print.

Chang, Daniel, Michael Keller, and Syed Hussaini. “Synthesis of Norbornene Derivatives for the Incorpoartion into the Matrix of Self-Healing Epoxies.” ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. Vol. 245. 2013. Print.

CHEM 2101 Sophomore Seminar
CHEM 3011 Organic Chemistry I Laboratory
CHEM 3013 Organic Chemistry I
CHEM 3021 Organic Chemistry II Laboratory
CHEM 3023 Organic Chemistry II
CHEM 4871 Senior Seminar I
CHEM 4872 Introduction to Research
CHEM 4981 Undergraduate Research
CHEM 7113 Physical Organic Chemistry
CHEM 7983 Research and Thesis
CHEM 9981 Research and Dissertation
TURC 1981 TURC Junior Scholar